Polycystic ovary syndrome, or PCOS, is a frequent cause of ovulatory infertility, but treatments ranging from lifestyle modifications to medications are often effective in restoring fertility, according to the National Institutes of Health. In particular, loss of 5 percent of body weight is often sufficient.
In one study cited by the National Institutes of Health, of 11 women with PCOS who experienced menstrual irregularities, nine either became pregnant or restored more normal menstrual cycles after losing 5 percent of their initial weight. In light of this, many doctors recommend lifestyle changes, including weight loss, exercise and cessation of smoking, as an initial approach to infertility from PCOS. If lifestyle changes are unsuccessful or insufficient, several medications are also available, according to the Mayo Clinic and WebMD, with in vitro fertilization being another option if medication fails.