It is possible to burn 3,500 calories per week when combining diet, strength training and cardiovascular activity together, according to Mayo Clinic. An individual must burn at least 500 calories per day to lose one pound, or 3,500 calories in a week.
The Mayo Clinic suggests cutting 500 calories out of a normal diet and reducing the amount of processed foods to help lose weight.
A strength training plan should be added to a person's weekly schedule also, when weight loss is desired. The Mayo Clinic recommends strength training at least twice per week. Additionally, to effectively lose weight, individuals should perform at least 300 minutes of cardiovascular exercise each week.