Severe thigh pain can be caused by many conditions, such as deep vein thrombosis, muscle cramping and neuropathy. Causes of thigh pain can generally be classified as having a neurological, musculoskeletal or vascular basis, according to Medical News Today.
Thrombosis is a condition that can cause severe thigh pain resulting from a blot clot that forms in a deep vein. Deep vein blood clots are normally formed in the lower leg or the thigh, although they can develop in other areas. This condition is more commonly experienced in people aged 60 and above, states Healthline.
Muscle cramping can cause severe thigh pain and sudden, uncontrollable contractions in the muscles. The contractions cause pain and can affect a variety of muscle groups, such as those in the front and back of the thigh and in the lower leg. Muscle cramping in the thigh can cause sharp and sudden pains that can last from seconds up to 15 minutes. These painful cramps may be accompanied by a bulge in the muscle below the skin’s surface. Muscle cramps that cause severe thigh pain can often be attributed to excessive exercising, dehydration, injury, poor blood supply or medical conditions, explains Healthline.
Radiculoplexus neuropathy is a condition common in older adults and type two diabetics. This condition can cause severe thigh pain by affecting the nerves. Sudden pain is usually experienced on one side of the body, although both sides can be affected. Other symptoms such as weight loss, atrophied muscles and mobility problems may also be associated with this condition, according to Mayo Clinic.