It is advisable to let a blister heal naturally, but it can be punctured if it is large and painful, according to WebMD. Blisters may not require medical attention, since the body absorbs the fluid in the blister, allowingÂ the skin on the blister to dry.
When popping a blister, it is necessary to use a sterilized tool. A person should wash the hands before puncturing the blister. A white or yellow fluid means that there is an infection, which might require medication. The top skin on the blister should not be removed, since it offers protection to the blister area. An antibiotic cream can be also applied to the area to prevent infections.