A peripheral giant cell granuloma is an oral cell lesion that normally emerges as a purplish-red nodule consisting of giant cells with more than one nucleus, states the National Center for Biotechnology Information. Although the cause of the granuloma is not definitively known, trauma and local irritation may stimulate its growth.
Peripheral giant cell granuloma, which resembles central giant cell granuloma, is one of the most common giant cell lesions that affect the soft tissue of the mouth. The granuloma consists of red blood cells that have been forced out of the arteries and into an area where the lesion forms. Other than trauma, dental implants may also cause the lesion, states NCBI.
Peripheral giant cell granuloma may start as a small swelling on the jaw and increase to up to 2 centimeters in size. These lesions, which can occur throughout life, are more common in women and in people between ages 30 and 40. The occurrence of the lesion is more common in the lower jawbone than in the upper jawbone. For treatment, physicians place the patient under local anesthesia and incise the overlying mucosa. Thereafter, the surgeon separates and removes the lesion from the adjacent tissue, explains NCBI.