Tablets, suppositories, and vaginal creams such as Monistat are all common over-the-counter medications for yeast infections, explains WebMD. Most yeast infections can be treated with over-the-counter medications.
When using a vaginal cream to treat a yeast infection, it is important to read the instructions carefully, as different brands have different application methods, according to WebMD. Creams are applied both around and into the vagina. Suppositories and tablets are also used to treat a yeast infection and are inserted into the vagina. In this case, they dissolve due to body heat, and the medication is absorbed into the system. Usually, tablets and suppositories treat the infection faster and are not as messy as creams.