Take over-the-counter drugs containing acetaminophen or ibuprofen for pain relief in the event of a wasp sting, according to WebMD. Antihistamines are also available over the counter and offer itch relief for wasp sting victims. Apply antibiotic cream directly to the wasp sting immediately after the incident.
In the event of a wasp sting, immediately pull out the stinger and apply ice, advises WebMD. Wash the sting site, then apply an antibiotic cream, such as Neosporin. Most of the time, wasp stings do not require additional medical treatment unless the person is allergic. Antihistamines, such as Claritin or Benadryl, are available over the counter to relieve itching and may help alleviate allergic reactions; however, allergic reactions to wasp stings require immediate medical attention.
Wasps deliver venom using their stingers as a form of offense and defense, according to About.com. Wasp stings can be very painful due to the wasp venom. The venom breaks down cell membranes within the body to send signals to the brain, which are experienced as pain. Other components of the venom act to stop the flow of blood to extend the feeling of pain and spread the venom to other cells; however, the amount of actual physical damage from a wasp sting is minimal.