Lamisil, Lotrimin, Micatin and Mycelex are over-the-counter antifungal creams that are recommended by WebMD. More severe cases of skin fungal infections may require prescription oral or topical antifungal medication.
Common cases of skin fungal infections include athlete's foot, ringworm and yeast infections, according to WebMD. Most cases of athlete's foot respond well to over-the-counter topical treatments, but severe cases usually require prescription oral medication. Prior to applying athlete's foot medication, users must wash and dry the affected area with a clean towel. Like athlete's foot, most ringworm infections respond well to over-the-counter treatment. Severe cases may call for prescription-strength antifungal creams or oral medications. Treatment for yeast infection varies depending on the type of infection.