According to the Advantix manufacturer, Bayer HealthCare, Advantix is waterproof and there is "no need to reapply the product after weekly swimming or a bath." For best results, Bayer recommends using a non-detergent shampoo while bathing the dog.
Advantix for dogs is specially designed to meet the health needs of canines. Bayer warns pet owners to never use Advantix on dogs younger than seven weeks old or cats. Owners must be sure to choose the appropriate dose for the dog based on its body weight. Advantix must be applied monthly. For the most effective treatment, owners need to apply Advantix on the same day each month to ensure continuing flea and tick protection.