Non-hemolyzed blood is blood in which the red blood cells remain intact, and is important for blood testing. Certain conditions can cause the red blood cells to break down prematurely resulting in hemolysis, or hemolyzed blood.
Non-hemolyzed blood is expected when studying a blood sample. Once red blood cells begin to break down, usually after 110 to 120 days, they are removed from the blood plasma by the spleen. However, there are several conditions that can cause the cells to break prematurely and appear in a blood sample, such as autoimmune disorders and infections. Also, how a sample is collected and processed can affect the cells within the sample, as extreme temperatures can cause blood to hemolyzed as well as defective collection equipment.