Hydroco/APAP 5-325, Norco, requires a prescription because it is classified as a Schedule III controlled substance by the U.S. Drug Enforcement Administration. The numerals are indicative of the dosage of each medication, 5 milligrams of hydrocodone bitartrate and 325 milligrams of acetaminophen, present in the tablet, according to RxList.
Norco is prescribed to alleviate moderate-to-severe pain. Potential side effects include drowsiness, dizziness, anxiety, skin rash and nausea. Prolonged use frequently results in constipation, reports RxList. A tolerance for the drug develops over time, making it less effective and potentially leading to overuse or abuse. Physical dependence may develop with several weeks of consistent use, which results in withdrawal symptoms upon cessation.