Flonase and Dymista are brand name medications that contain fluticasone propionate, according to the manufacturers. Fluticasone propionate is also sold as a generic nasal spray.
Fluticasone propionate is the active ingredient in Flonase, states the manufacturer. It treats itchy and watery eyes, itchy nose, sneezing, runny nose and nasal congestion. Flonase offers 24-hour relief to adults and children 4 years of age and older. It is available over the counter and by prescription.
The other active ingredient in Dymista is azelastine hydrochloride, which is an antihistamine, states WebMD. Dymista treats nasal congestion, runny nose, sneezing, itchy nose and itchy, watery eyes in adults and children 6 years old and older. It provides relief for 12 hours and is available by prescription.
Fluticasone propionate is a synthetic corticosteroid with anti-inflammatory properties, notes DailyMed. It is used for the management of perennial and seasonal allergic and nonallergic rhinitis in adults and children. It causes glucocorticoid receptors to produce a potent anti-inflammatory response to chemicals that cause inflammation, explains MedicineNet. Fluticasone propionate blocks histamines, cytokines and prostaglandins, asserts Flonase. It also blocks tryptases, chemokines and leukotrienes. However, the manufacturer notes that the exact mechanism of how this drug works on the body is unknown.