Some examples of prescription ear drops are amoxicillin, azithromycin, ceftriaxone, cefuroxime and clarithromycin. Amoxicillin, a penicillin class antibiotic, is most commonly used for ear infections. It is known as a reliable and cost effective antibiotic ear drop, but physicians may choose an alternative, depending on the infection.
Ceftriaxone, also called Rocephin, is a third generation cephalosporin. Cefuroxime, a second generation cephalosporin, has the trade name Ceftin. Azithromycin is also known as Zithromax, while Clarithromycin’s trade name is Biaxin. Biaxin and Zithromax are macrolide antibiotics.
Penicillin and cephalosporin class antibiotics inhibit bacterial cell wall synthesis. Penicillin and cephalosporin class antibiotics are effective against gram positive and some gram negative bacteria, such as E.Coli and Pseudomonas.
Macrolide antibiotics work by inhibiting bacterial protein synthesis in the bacterial ribosomes by binding to the 50s ribosomal subunit. Macrolide antibiotics are effective against bacteria such as Streptococcus, H. influenzae and S. aureus. Macrolide antibiotics are bacteriostatic. Bacteriostatic antibiotics halt the growth of bacteria, giving the body time to fight the infection by utilizing the immune response.
Penicillin and cephalosporin class antibiotics are bactericidal due to their selective destruction of bacterial cell walls by interfering with the function of a bacterial enzyme. Selection of antibiotics depends on the infecting organism and patient.