There is some evidence to suggest that multiple myeloma may be hereditary, according to the American Cancer Society. Specifically, people with multiple myeloma in their family history are four times more likely to contract the disease. However, the majority of people with multiple myeloma have no family history of this cancer.
Another genetic risk factor for multiple myeloma is race. African Americans are more than twice as likely to get multiple myeloma than white Americans, according to the American Cancer Society. The reason for this is not known and the cause of multiple myeloma is still unknown. However, it is known to develop from another condition called monoclonal gammopathy of undetermined significance, or MGUS.