To use ibuprofen safely, it is recommended you not increase the dosage set forth by your doctor, according to Mayo Clinic. It is further advised that the drug not be taken any more often or for any longer than what is prescribed by the doctor.
Ibuprofen is used for many different types of pain and inflammation, with dosage amounts varying accordingly. Long-term use of ibuprofen can cause heart and circulatory problems including heart attack and stroke, and it can cause stomach and intestinal issues such as internal bleeding and perforation of the bowels, according to Drugs.com. Follow the label on the bottle or ask a doctor to learn the proper dosage for ibuprofen.