The maximum daily adult dose of ibuprofen is 3,200 milligrams, according to Drugs.com. Individuals taking ibuprofen should use the smallest dose that brings pain relief.
For mild to moderate pain, Drugs.com recommends patients limit their ibuprofen dosage to 200 to 400 milligrams every six hours for a maximum of 2,400 milligrams daily. However, the lower dosage is sometimes not effective for conditions such as rheumatoid arthritis or osteoarthritis. A patient who takes the maximum dosage for an extended period should speak with his doctor about testing to determine if the medication is causing damage to his stomach or intestines. Taking ibuprofen with food or milk helps to reduce the chances of stomach problems.