Marplan, Nardil, Emsam and Parnate are monamine oxidase inhibitors, according to Mayo Clinic. Other MAOIs include Azilect, Eldepryl and Zelapar, claims MedicineNet. Monoamine oxidase inhibitors are the first types of antidepressants developed. They ease depression by affecting the neurotransmitters in the brain, says Mayo Clinic.
Due to Monoamine oxidase inhibitors having many dangerous side effects, such as high blood pressure, they have been replaced with safer antidepressants, as of 2015. They are, however, often used when other antidepressants do not work, says Mayo Clinic. Side effects of monoamine oxidase inhibitors include orthostatic hypotension, weakness, dizziness and drowsiness, claims MedicineNet. Headache, fatigue, agitation, anxiety and weight gain are also side effects of MAOIs.