It can be unsafe to drink grapefruit juice while taking certain statins. Medications such as Lipitor, Zocor and Prevachol can adversely interact with grapefruit juice, according to the Food and Drug Administration. Individuals should consult a doctor or pharmacist about possible drug interactions.
Statins are prescription drugs that help lower cholesterol, advises Healthline. They work with the liver to lower the amount of cholesterol the body makes. Fresh grapefruit and grapefruit juice increase the absorption of statins and other drugs into the bloodstream, explains FDA. This is due to a substance in grapefruit that hinders an enzyme responsible for controlling the amount of medication entering the bloodstream, states Healthline. Increased levels of statins in the bloodstream can lead to muscle breakdown, liver damage and kidney failure.