Vomiting and appetite loss are the most common side effects of Metacam, according to PetMD. Other side effects include diarrhea, bloody or black stools, behavioral changes, increased water intake and urinary changes. Skin irritation, jaundice, stomach ulcers and unexpected weight loss may also occur.
Metacam is an oral nonsteroidal anti-inflammatory drug for dogs that treats pain and inflammation due to osteoarthritis, explains Drugs.com. This medication is not for use in puppies less than 6 weeks old or in dogs that are breeding or nursing. It is not safe to treat humans or cats with Metacam. Renal failure and death may ensue if cats receive Metacam.