MegaRed is the brand name of a variety of omega-3 fatty acid supplements manufactured by Schiff. According to the manufacturer, the krill oil in MegaRed is extracted from krill harvested from the Antarctic Ocean. Schiff says that krill oil is more absorbable than fish oil, and taking one Megared pill per day will support heart and joint health.
Krill oil contains essential fatty acids that are similar to the fatty acids in fish oil, and it is taken for many of the same conditions as fish oil. The omega-3 fatty acids in these oils may improve symptoms of arthritis and improve the blood lipid profile, according to WebMD.
Schiff and other manufacturers of krill oil claim that fewer pills need to be taken relative to fish oil to produce a therapeutic effect. However, a study published in the journal Lipids reported that volunteers taking 3 grams of krill oil per day achieved the same concentration of omega-3 fatty acids in the blood as volunteers taking only 1.8 grams of fish oil per day.
A randomized controlled trial published in the journal Lipids in Health and Disease directly compared the effect of various sources of omega-3 fatty acids on blood lipid markers of cardiovascular disease risk. The products that were compared were krill oil, salmon oil, concentrated fish oil, and ethyl ester fish oil. The concentrated fish oil, said to provide a dose of 650 milligrams of EPA and 450 milligrams of EPA, was markedly superior to the other products in reducing markers of cardiovascular disease risk. Krill oil and unconcentrated fish oil (salmon oil), when taken at the dosages recommended by the manufacturer, did not affect the cardiovascular disease risk profile in any substantial way.