As of 2015, the medications doctors use to treat an inflamed bladder are pentosan polysulfate and dimethyl sulfoxide, according to University of California Los Angeles Urology. The U.S. Food and Drug Administration has approved both drugs. Interstitial cystitis has no cure and does not respond to antibiotic treatment.
Doctors give pentosan polysulfate, or Elmiron, to patients orally to reduce inflammation and coat the bladder lining, explains UCLA Urology. Patients receive doses of dimethyl sulfoxide through catheters that doctors insert directly into the bladder. Doctors administer the medication over intervals of several weeks to minimize pain and inflammation and destroy tissue-damaging free radicals. Interstitial cystitis requires individualized patient treatment plans because the condition has multiple causes.