What Medications Relieve Pain in the Knee?


Quick Answer

Medications for knee pain relief include over-the-counter drugs such as acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDS), glucosamine and chondroitin sulfate, according to Everyday Health. Prescription-strength nonsteroidal anti-inflammatory drugs and COX-2 inhibitors such as celecoxib also help relieve pain in the knee.

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Full Answer

Over-the-counter medications are suitable when the knee pain is mild, while prescription medications are suitable for moderate to severe knee pain because they are more effective than the former, explains Everyday Health. Other than prescription and over-the-counter drugs, injectable medications such as corticosteroids and viscosupplementation are also applicable in the alleviation of knee pain, especially, severe pain, and are typically used as the last step before surgical replacement of a knee joint.

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