Medications that relieve bone pain in the legs include non-steroidal anti-inflammatory drugs, or NSAIDs, analgesics, opioids and bisphosphonates. Fractures, metastatic cancer and Paget's disease are some of the underlying causes of bone pain in the lower limbs.
Pain in the leg occurs when the muscles, bones, tendons, blood vessels and nerves comprising this anatomical structure undergo tremendous stress or are adversely affected by certain medical conditions. Bone pain in the leg can result from injuries where the bones completely splinter.
Physicians generally recommend intake of over-the-counter oral medications, such as acetaminophen, to relieve the immediate pain that ensues after a fracture incident. NSAIDs, such as ibuprofen, naproxen and aspirin, are also nonprescription drugs that relieve pain and reduce swelling. More potent analgesics may be prescribed for intense discomfort, as claimed by Mayo Clinic.
Bone pain that originates from Paget's disease is caused by tiny breakages that primarily occur in bones that support the weight of the body, including the legs. NSAIDs and prescription drugs can be taken to relieve the pain, according to the Osteoporosis and Related Bone Diseases National Resource Center of the National Institutes of Health.
The lower limbs are typical sites for bone metastases, as stated by Texas Oncology. Pain medications are usually based on the level of pain a cancer patient experiences. Strong opioids, including morphine, methadone and oxycodone are given to patients with severe pain.