Medications that improve blood circulation sometimes help alleviate the symptoms of cold hands and feet if these symptoms are linked to poor circulation in the extremities, according to Mayo Clinic. Some forms of anemia and neurological disorders also cause cold hands and feet, and the symptoms may abate with proper medication of these conditions.
One disease of blood circulation linked with the symptoms of cold hands and feet is Raynaud's disease, explains Mayo Clinic. This condition appears to be linked to spasms in the blood vessels that restrict blood flow, and sufferers often experience color changes and prickling sensations in the affected limbs. Family history and living in cold climates are often linked to Raynaud's disease, as are smoking and exposure to repetitive stress and vibrations.
The use of certain drugs such as beta blockers and some over-the-counter medications for cold that constrict the blood vessels may contribute to Raynaud's disease in some people, notes Mayo Clinic. Medications such as alpha blockers, calcium channel blockers and vasodilators help to the prevent spasms associated with Raynaud's disease and relax the blood vessels in the arms and legs, restoring normal blood flow and reducing the feelings of cold in the hands and feet.