A mean platelet volume (MPV) test that is abnormally high can be an indication of medical conditions such as immune thrombocytopenic purpura and Bernard- Soulier disease, as noted by Lab Tests Online. The MPV count is a blood component measured as part of a complete blood count (CBC). The MPV count is the average size of blood platelets in the body, and a high count can lead to blood clotting problems.
In adults and children, the normal range for MPV is between 7.4 and 10.4 femtoliters, according to WebMD. Bernard- Soulier syndrome is a hereditary bleeding disorder in which platelets are quite large, which causes excessive bleeding because blood does not clot properly. The cause of Bernard- Soulier syndrome is the transmission of recessive genes to an offspring from both parents. This condition is also referred to as giant platelet syndrome.
Besides bleeding and bruising, some other symptoms are easily bruising, bleeding gums and nosebleeds. Patients with this condition may not require medication normally, as stated by eMedicine - Medscape. Similarly, patients may not take medications that affect blood's clotting ability, such as aspirin.
Because there are other platelet disorders, such as idiopathic or immune thrombocytopenic purpura, that can present similar symptoms, it is important to diagnose these different conditions properly to ensure the appropriate treatment options. The exact cause of idiopathic thrombocytopenic purpura, which is another bleeding disorder, is not entirely known.