Hypertrophy-specific training programs need to be tailored to the individual, according to Bodybuilding.com. During the five-repetition period, the number of sets should be maximized while avoiding injury and muscular failure due to fatigue.
Bodybuilding.com describes the HST program as a training technique designed to add muscle bulk to the body. Each muscle group is worked three times per week. The amount of weight lifted is progressively increased for six to eight weeks of training, while the number of lifts performed per set is progressively reduced. A rest period of nine to 16 days is then introduced, followed by another period of training.