In the United States, approximately 1 million people have Paget’s disease, according to the National Institute of Arthritis and Musculoskeletal and Skin Diseases. Men, the elderly and people of Northern European descent are more likely to develop the disease, which causes enlarged, weakened bones.
Individuals with Paget's disease experience symptoms such as broken bones, cartilage damage in the joints and pain, although some people have mild symptoms and may be unaware that they have the disease, explains the National Institute of Arthritis and Musculoskeletal and Skin Diseases. Doctors typically use X-rays to diagnose Paget's disease. As the disease develops, it can lead to other diseases and disorders, such as arthritis, heart disease, kidney stones and loss of hearing.