There are approximately 329 calories in a 1-cup serving of spaghetti with meat sauce, according to FatSecret . This figure includes 118 calories from fat.
A serving of spaghetti and meat sauce contains 13.06 grams of total fat, which represents 20 percent of the daily values of fat recommended for most people. Of that fat, 4.34 grams is saturated fat, 1.339 grams is polyunsaturated fat and 5.638 is monounsaturated fat. The same serving contains 51 milligrams of cholesterol, 1887 milligrams of sodium, 811 milligrams of potassium and 33.33 grams of carbohydrates. There are 3.9 grams of dietary fiber and 20.22 grams of protein in one cup of spaghetti and meat sauce, according to FatSecret .