For most people, walking briskly on a treadmill for 60 minutes burns off 300 to 400 calories. Some interval training programs that involve alternating between running and jogging on a treadmill can burn around 500 calories in 60 minutes.
The number of calories burned on a treadmill depends on a number of factors, such as the weight of the user, how the user moves, and the intensity and duration of the exercise. The intensity is raised by increasing the speed and incline of the treadmill. The number of calories burned that is displayed on a treadmill's digital screen is not typically very accurate unless the calculation includes information such as the user's weight and data from a heart rate monitor worn by the user.