The number of calories in a typical 750-milliliter bottle of wine depends on the type of wine. Light-colored wines, such as white wines, contain approximately 600 calories per bottle. Intense red wines usually contain up to 200 calories per glass, or about 1,000 calories per bottle.
The main source of calories in wine is alcohol. Red wines, such as pinot noir and syrah, have more alcohol, so they contain more calories than white wines, such as Riesling and pinot grigio. American wines tend to contain more calories than wines from European countries, such as Italy, France and Germany, for the same reason.