Isolated instances of simple yeast or mold infection of the lungs--called aspergillosis--usually require no treatment unless they cause other serious symptoms, according to Mayo Clinic. However, invasive aspergillosis requires treatment with antifungal medicines, according to the United States Centers for Disease Control and Prevention.
In most cases, aspergillosis that does not cause the patient to cough up blood due to internal bleeding is usually left untreated, or treated with occasional doses of antifungal medication, according to Medline Plus. In some cases, anti-fungal medications may be supplemented by corticosteroids to improve lung function, according to Mayo Clinic. Antifungal drugs such as voriconazole, itraconazole and micafungin are used to combat severe mold infection, according to the CDC. In rare cases where the internal bleeding is uncontrollable, a patient may need to undergo surgery to remove the mold or block the artery at the site of the infection.
Patients with weakened immune systems require special treatment because common anti-fungal drugs such as voriconazole and amphotericin B may cause side effects and adverse reaction in patients who take immunosuppressant drugs, according to Mayo Clinic. Surgery for lung yeast infections is considered risky because of its complexity and the medical complications associated with the procedure.