Low iron saturation is another way of saying someone has low levels of iron in their blood or has iron-deficiency anemia, according to the American Society of Hematology. Iron deficiency is very common in women, especially those who are menstruating, pregnant or breastfeeding.
Experiencing physical trauma, undergoing surgery and being vegetarian also increase the risk for iron-deficiency anemia, notes the American Society of Hematology.
Because anemia tends to develop slowly, many people who suffer from anemia don't realize it until the condition worsens, according to WebMD. Those who suffer from anemia, in its mature form, may feel weak or tire out easily, be grumpy or cranky, look very pale and have trouble concentrating.