The treatment time for collagenous colitis varies, according to Mayo Clinic. Treatment is not standardized due to a lack of large-scale placebo treatment trials, and collagenous colitis can get better over time without treatment. Collagenous colitis occurs when a layer of collagen lines the colon, causing inflammation and diarrhea.
When symptoms are prolonged or more severe, doctors prescribe treatment on a step-by-step basis, starting with the simplest treatment, according to Mayo Clinic. A low-fat, low-fiber diet, as well as discontinuing an existing medication regiment are usually suggested first, followed by medication targeting the diarrhea symptoms. Surgery is rare and reserved for the most severe cases.