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What are the long-term effects of Zoloft?

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Quick Answer

Zoloft may increase the risk of suicidal thoughts and behaviors in people younger than 24 years old, according to Everyday Health. It may also cause harm to a developing fetus during pregnancy. The development of the potentially life-threatening serotonin syndrome is also a possibility, reports Drugs.com.

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Full Answer

People younger than 24 are at risk of developing worsened depression or other psychiatric problems while taking Zoloft, explains Everyday Health. Such effects may include anxiety, agitation, panic attacks, insomnia and irritability, among others, notes Drugs.com.

The risk of developing serotonin syndrome also increases while taking Zoloft. Increasing serotonin is a way to treat depression, but overdosing on it can cause this potentially life-threatening condition, reports Everyday Health. Symptoms may include mental state changes, autonomic instability, neuromuscular symptoms, seizures and gastrointestinal symptoms, explains Drugs.com.

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