It can take several weeks or even months for Retin-A to begin working, according to Drugs.com. Individuals who do not see a clear improvement in their acne within 8 to 12 weeks should contact their physician.
Retin-A is a medication used to treat acne, says WebMD. This treatment, sometimes referred to as tretinoin, is a form of vitamin A that allows the skin to renew itself. Individuals using the medication to treat acne may notice a temporary period of worsening symptoms before beginning to see improvement. For optimal results, individuals should avoid washing the area, or applying other skin treatments, that the Retin-A is applied to for at least one hour.