The recovery time following a prostate biopsy is several days, according to Mayo Clinic. Most people feel slight soreness or experience some light rectal bleeding or blood in the stool or urine for a few days following the procedure.
Some people may notice a rust- or red-colored tint to their semen for several weeks after their biopsies, notes Mayo Clinic. Patients should notify their doctors if they experience heavy or prolonged bleeding, worsening pain, difficulty passing urine or swelling near the area of the biopsy. Although most people take an antibiotic for a few days following the procedure, patients should also notify their doctors right away if they experience any signs of infection, such as painful urination, fever or penile discharge.