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How long does it take for minocycline to work?

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The length of time required for minocycline to clear an infection depends on the condition for which the medication is prescribed, explains Drugs.com. Symptoms of the infection may improve before the infection is completely cleared, so it is necessary to take the medication for the prescribed amount of time.

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Typical minocycline treatment for acne is a 50-to-100 milligram tablet twice a day for three-to-six weeks followed by a single daily maintenance dose of 50-to-100 milligrams, according to Drugs.com. Skin and soft tissue infections caused by the bacterium Mycobacterium marinum generally require at least three months of treatment with minocycline, and meningococcal meningitis normally requires five days of the drug.

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