WebMD states that impetigo sores usually completely heal in a week. Impetigo begins to heal noticeably after three days of treatment. This healing time period is the same for mild cases of impetigo that require only an antibiotic cream or for serious cases that require antibiotic pills as well.
WebMD recommends that patients clean impetigo sores with soap and water and soak them in warm water for 15 minutes before applying doctor-prescribed antibiotic cream to hasten the healing process. Scratching prolongs the healing process and spreads infection to other areas of the body. Using the same washcloths and sheets before treatment can extend the healing process due to reinfection.