Focalin XR has a half-life of approximately two to four and a half hours, which means it is detectable in the body for up to 27 hours, according to HealthCentral. The half-life of medication is not exact because it depends on each person's metabolism and health.
Focalin XR is a brand name for the generic drug dexmethyfenidate HCL, reports DailyMed. It is a central nervous system stimulant prescribed for attention deficit hyperactivity disorder. Chronic abuse can lead to psychological dependence, tolerance and abnormal behavior. Withdrawal symptoms such as depression and suicidal thoughts may occur if the patient suddenly discontinues use of Focalin XR, explains WebMD. Reducing the dosage gradually is the recommended approach.