How Long Does It Take for Clindamycin Phosphate to Clear Acne?

It can take two to six weeks for clindamycin phosphate to begin producing results and up to 12 weeks for it to produce a complete benefit in clearing acne, according to WebMD. If acne does not improve within this period, contacting a doctor to discuss further treatment is recommended.

Clindamycin phosphate is an antibiotic that helps diminish acne by preventing the growth of bacteria that causes it, according to WebMD. A topical medication, clindamycin phosphate is used by applying a thin layer of the lotion to the affected areas. Some common side effects to this medication include burning, itching, peeling skin and redness.