Liver disease may cause abdominal pain, according to MedicineNet.com. Abdominal pain located specifically in the right upper quadrant is considered a classic symptom of liver disease.
Other symptoms that may accompany liver disease include nausea, vomiting and jaundice, according to MedicineNet.com. Fatigue, weakness and weight loss may also occur with liver disease. However, as liver disease is a catch-all term that applies to many kinds of liver problems, other symptoms may arise depending on the specific type of liver disease that an individual acquires. Additionally, approximately three-quarters of the liver tissue must be affected before an individual presents with symptoms.