No one knows exactly how lithium orotate works, though researchers believe it may help mental disorders by increasing the level of activity of the chemical messengers in the brain, according to WebMD. This medication is commonly used for bipolar disorder, depression and schizophrenia.
There is not a lot known about the safety of lithium orotate, explains About.com. There is evidence, however, that long-term use of this medication may be dangerous thanks to a study from the Journal of Medical Toxicology. This study shows that tremors and nausea may occur when taking this medication for a long period of time. It also may cause kidney damage over time if not monitored.
In addition, this medication may cause symptoms that are similar to those experienced with lithium toxicity, states About.com. In addition to symptoms such as vomiting and nausea, patients who experience lithium toxicity may experience long-lasting neurological issues such as dementia and tremors as well as heart issues such as cardiac arrhythmias. Since these conditions are potentially very dangerous, periodic blood testing is recommended for patients taking lithium to ensure levels of the drug are not within a toxic range. It is also important to remember that this drug can have serious consequences, so only use it under the care of a doctor.