Lipozene is a weight-loss supplement developed by the Obesity Research Institute. The active ingredient is glucomannan which, according to Newsmax Health, is a water-soluble fiber derived from the konjac plant. Insufficient research exists to support weight loss claims, states WebMD.
Water-soluble fibers expand after absorbing water in the digestive tract, explains WebMD, which leads to a sensation of fullness. Newsmax Health reports that glucomannan does reduce the absorption of carbohydrates and cholesterol and helps maintain blood sugar levels. The weight-loss effects of Lipozene marketed by the Obesity Research Institute are said to be a result of naturally reduced portion sizes.