What is Lipodissolve?


Quick Answer

Lipodissolve is a series of medicine-containing injections purported to dissolve small areas of fat, according to Your Plastic Surgery Guide. Lipodissolve is also known as mesotherapy, lipozap, lipotherapy and injection lipolysis, states the U.S. Food and Drug Administration. Phosphatidylcholine and deoxycholate are the active agents in the injections.

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Full Answer

Lipodissolve works through the activity of deoxycholate, which breaks down the fat cells, explains the Journal of Clinical and Aesthetic Dermatology. Phosphatidylcholine aids the digestion and drainage of released fat and protects nearby mucosa from deoxycholate’s corrosive action. Less bruising, pain and tissue hardening occurs when phosphatidylcholine is in the injection. In addition to these drugs, practitioners add other ingredients, including vasodilators, collagenase, L-carnitine, hyaluronidase and aminophylline.

The areas of treatment are the abdomen, flanks, posterior upper thighs, outer thighs and anterior thighs, states the Journal of Clinical and Aesthetic Dermatology. The back, chin, jowls and arms are less common areas of treatment.

The safety of lipodissolve is unknown, and patients report complications and adverse effects such as pain, skin infection, ulceration, abscess and necrosis, according to the U.S. Food and Drug Administration. As of 2015, neither phosphatidylcholine nor deoxycholate is an approved drug in the United States for the purpose of eliminating fat. Additionally, the Food and Drug Administration has not approved lipodissolve.

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