The average 5-year survival rate following a diagnosis of chronic lymphocytic leukemia, or CLL, is between 50 and 80 percent, according to Healthline. Survival at the 10-year mark is around 34.8 percent for both CLL types.
The prognosis of CLL is affected by several factors, notes Healthline. Advanced age, high blood levels of beta-2-microglobulin and deleted chromosomes 17 and 11 in the leukemic cells all contribute to a poor prognosis. People with CLL cells containing low levels of CD38 or ZAP-70 proteins or with a deletion on part of chromosome 13 have a better prognosis. Although there is no cure for CLL, there are treatment options that can enhance life expectancy and help those afflicted with the condition lead a better quality of life.