Leg pain is one of the symptoms of bone cancer, according to Mayo Clinic. Injuries to bones, muscles, tendons or ligaments cause most cases of leg pain, but back problems, circulation issues, arthritis, blood clots and fibromyalgia are some other common causes.
If bone cancer develops in the leg, pain is likely to be present, indicates the American Cancer Society. The pain may be intermittent at first or only occur when the leg is used. As the cancer progresses, pain may become more constant. A swelling, lump or mass may develop in the leg if bone cancer is present. Other symptoms of cancer include fatigue and weight loss.
Bone cancer in the leg can cause weakening of the leg bone, and fracture is possible but not common. If the bone cancer develops near one of the joints, the individual may experience stiffness, swelling and pain in the joint that limits range of motion, notes the American Society of Clinical Oncology. In rare cases, people with bone cancer develop a fever and anemia. Diagnosis of bone cancer involves imaging tests, such as X-rays, CT scans, MRIs and bone scans. Depending on the results of the imaging tests, a doctor may perform blood tests and a biopsy.