Laser treatment for spider vein removal is not very effective, and, therefore, it is recommended that patients receive sclerotherapy for spider vein removal, according to WebMD and the American Society of Plastic Surgeons. Laser treatment is also an option for spider veins, but is not nearly as effective.
Sclerotherapy targets spider veins specifically by injecting a solution into the vein in order to force it to break down, according to WebMD. In sclerotherapy, results last for an average of two years, and the treatment offers an average of 90 percent improvement, according to WebMD. Spider veins appear on the legs as red, purple or blue vein clusters. They tend to appear on calves, ankles and thighs. Spider veins appear due to hormonal issues, genetics, weight fluctuation, prolonged standing and prolonged sitting, according to the American Society of Plastic Surgeons.