Blood tests that measure liver enzymes are among the diagnostic tools doctors use most frequently to detect liver disease, according to WebMD. Liver enzyme testing may occur during a routine physical or when a patient exhibits possible symptoms of liver dysfunction, such as jaundice, abdominal pain, nausea or vomiting.
In healthy individuals, liver cells contain liver enzymes. A damaged or injured liver leaks enzymes into the bloodstream, and blood tests can detect them, reports WebMD. Other tests that may be useful in diagnosing liver disease are prothrombin time, which measures the amount of time it takes for blood to clot, and tests for albumin and bilirubin levels.