Kre-Alkalyn is a creatine monohydrate compound that is buffered for stability, according to the manufacturer. WebMD reports that taking creatine monohydrate before an athletic event can improve performance, particularly in brief high-intensity events such as sprinting.
A study published in the Journal of the International Society of Sports Nutrition reported no difference in efficacy or safety for buffered creatine as compared to creatine monohydrate. WebMD says that creatine supplementation is allowed by most sports regulating bodies because its use does not appear to be harmful. Creatine use does not appear to improve performance in aerobic or endurance events. Extremely high doses of creatine may be detrimental to the kidneys. People taking creatine may gain weight due to water retention in the skeletal muscles.