Knots in the palm of the hand can be a symbol of Dupuytren's contracture, according to WebMD. A characteristic of this disorder is abnormal thickening of the fascia beneath the skin of the palm.Continue Reading
An initial symptom of Dupuytren's contracture is multiple knots or lumps under the hand, which may cause discomfort at first. When people have Dupuytren's contracture, the fibers that run from the palm to the fingers tighten and can cause the fingers to curl forward or can cause hand deformities, in serious cases, states WebMD. The pinkie and ring finger are more likely to curl than other fingers, and it may affect both hands. People who have this disorder may have a difficult time picking up objects, wearing gloves or shaking hands.
The cause of this disorder is unclear, but those who drink a lot of alcohol and those who suffer from diabetes or epilepsy may be more likely to develop the condition, explains WebMD. This disorder runs in families and is more likely to occur in those over age 40 and people who have a Northern European or Scandinavian heritage. There is no cure for Dupuytren's contracture, but treatments such as corticosteroid injections may be helpful in reducing swelling of the nodules.Learn more about Pain & Symptoms